06
Mar
A recent study out of Rush University Medical Center in Chicago and published in the journal Neurology reports that deaths due to Alzheimer’s disease are greatly under-reported. The death certificate and medical records of Alzheimer’s patients frequently list the immediate cause of death, such as pneumonia, rather than the underlying cause, which is the inability to fight…more »
26
Feb
On February 10, 2014 the ALZFORUM (www.alzforum.org) highlighted work by a team from Columbia University showing that astrocytes, a specialized type of glia cell, cause the death of motor neurons in an in vitro study of cells from ALS patients. The authors of the study are now trying to identify the toxic factor that astrocytes…more »
26
Feb
GliaCure President Phil Haydon recently co-authored a review in the journal Neuron on gliotransmitters and the interplay between glia and neuron in signaling in the brain.
05
Feb
On February 4, 2014 the National Institutes of Health (NIH) announced the formation of the new Accelerating Medicines Partnership (AMP) to focus on three areas of research, including Alzheimer’s disease. This partnership, which brings together high level government entities, 10 biopharmaceutical companies and several non-profit organizations, is intended to identify and validate biomarkers of disease…more »
09
May
A manuscript published in the May 5 edition of Nature Medicine documents research findings that stimulating endogenous ATP release from astrocytes induces antidepressant-like effects in mouse models of depression. The authors summarize their study by stating that: “Understanding the mechanisms that underlie the antidepressant-like effect of ATP may allow the identification of new targets for…more »
19
Mar
A new study recently published by GliaCure President Phil Haydon’s research lab at Tufts University indicates that astrocytes play a vital role in the spread of damage after stroke. This study, published in The Journal of Neuroscience, suggests that, while researchers have previously focused on the role of neurons and their release of neurotransmitters in…more »
30
Jan
GliaCure President Phil Haydon’s research laboratory at Tufts University has published a study showing that glia may provide the key to a novel treatment for depression. It has long been known that a total night of sleep deprivation has a fast-acting antidepressant effect; however, the mechanism underlying this effect was not understood. The Haydon group…more »
03
Dec
The New England Journal of Medicine recently included papers detailing research from two groups pointing to a mutation in the gene TREM2 as a risk factor for Alzheimer’s disease. This mutation appears to lead to inflammation of the brain and decreased clearing of amyloid beta plaques. In discussing these papers Harald Neumann and Mark J.…more »
17
Jun
GliaCure is preparing for the 2012 BIO International Convention that runs from Monday, June 18 through Thursday, June 21 in the Boston Convention & Exhibition Center in the Boston Innovation District. GliaCure has set up its booth at the Convention Center and will be participating in more than 20 partnering meetings. Check back for pictures…more »
07
Jun
On May 10, 2012 an article by was published by a research group in the journal Cerebral Cortex. This paper details a study in human brain tissue showing that bidirectional signaling takes place between neurons and astrocytes. Cerebral Cortex is not an open access journal, so the full report is available only to subscribers; however,…more »