New publication supports GliaCure’s approach to depression

A manuscript published in the May 5 edition of Nature Medicine documents research findings that stimulating endogenous ATP release from astrocytes induces antidepressant-like effects in mouse models of depression. The authors summarize their study by stating that:

“Understanding the mechanisms that underlie the antidepressant-like effect of ATP may allow the identification of new targets for the treatment of depression.” (Cao et al, 2013).

These findings corroborate the recently-published studies on the role of glia in depression from GliaCure President Phil Haydon’s group (Translational Psychiatry, Hines et al, 2013) and provide additional validation for GliaCure’s approach to developing new therapeutics for major depressive disorders.